Patient-specific 0D–3D modeling of blood flow in newborns to predict risks of complications after surgery

Abnormal developments of the cardiovascular system are common congenital malformations. Computational fluid dynamics and mathematical modeling can be used to perform quantitative predictive assessments hemodynamic properties in varied conditions. This article addresses development a coupled 0D–3D model blood flow newborns predict risks complications after surgery. The 0D-model systemic circulations is created by using analogy between vessels current through an electric circuit. A shunted section aorta pulmonary artery replaced with 3D-model two-way fluid-solid interaction (FSI).A vessel aortic valve examined separate 3D-model. Three-dimensional geometry based on real CT-scans patient. algorithm for coupling models different levels relies meeting condition that pressures volumetric flows equal at boundary. We have developed identifying personal parameters from results obtained solving optimization problem. experiments individual made it possible analyze velocities, near-wall stresses, flows, deformations. Observable stresses considered risk factors could cause calcification leaflets other diseases. solutions “aorta – shunt artery” 3D-system allowed obtaining spatial distributions pressures, significant respect probable pathology development. approaches primarily relevant decision-making surgical practice postoperative complications. In future, our plans develop so covers also saturation oxygen exchange. necessary assessing whether supply lungs adequate.